AC Immune, Nestlé Institute Partner to Develop Alzheimer’s Diagnostic

AC Immune will partner with the Nestlé Institute of Health Sciences (NIHS) to develop a new minimally invasive Tau diagnostic assay for early diagnosis of Alzheimer’s disease.The research collaboration—whose value was not disclosed—is designed to combine AC Immune’s lab capabilities and expertise in the biology and pathology of Tau with NIHS’ multiplexed antibody technology platform.

NIHS’ antibody technology was developed by its Prometheus Laboratories subsidiary, and is being applied by the institute in Brain Health research, specifically in Alzheimer’s. According to the institute, the assay uses an antibody microarray-based platform that measures the expression and activation of target proteins in tissues, blood, and other fluids.

The partners said they intend to identify and validate a highly sensitive diagnostic assay for detecting Tau in human cerebrospinal fluid and blood plasma.

“Our overarching goal is to develop nutritional approaches and technologies that help people maintain or re-establish their cognitive vigor,” Prof. Emmanuel E. (Ed) Baetge, Ph.D., director of NIHS, said in a statement. “This collaboration agreement opens up exciting new possibilities in the quest to better understand and combat this debilitating disease.”

Added Prof. Andrea Pfeifer, Ph.D., CEO of AC Immune: “Early diagnosis of this critical global health problem is equally needed for the development of pharmaceutical as well as nutritional approaches.”

Portrait of an Alzheimer’s Patient – YouTube

Dr. Pfeifer also said the collaboration with NIHS marks AC Immune’s fourth partnership involving the Tau protein. The company’s three other partnered programs targeting Tau include the Phase Ib vaccine ACI-35, co-developed with Johnson & Johnson’s Janssen Pharmaceuticals; Tau PET tracers co-developed with Piramal as an Alzheimer’s diagnostic agent; and preclinical Tau-antibodies co-developed with Roche’s Genentech.AC Immune focuses on designing, discovering, and developing therapeutic and diagnostic products designed to prevent and modify neurodegenerative diseases caused by misfolding proteins. Founded in 2003, AC Immune has raised CHF 84 million ($86.5 million) from private investors.

 




16,707 thoughts on “AC Immune, Nestlé Institute Partner to Develop Alzheimer’s Diagnostic

  1. Its like you read my thoughts! You seem to know so much approximately this, like
    you wrote the guide in it or something. I feel that
    you simply could do with a few % to force the message home a little bit, but instead of
    that, this is great blog. A fantastic read.

    I’ll definitely be back.

  2. I had gotten that gifts for the our mother for the Xmas due she is the jewelry freak. The particular something she does not put on a great deal concerning was, bracelets. I bought the lady this particular charm bracelet furthermore after she opened it yesterday she absolutley enjoyed it! This time the problem are, the lady getting things regarding furthermore off of by just by herself. Haha… general great system, things delivered additionally came incredibly very early additionally the mom was experiencing it. Thank your.

  3. certainly like your web-site however you need to check the
    spelling on quite a few of your posts. Many of them are rife with spelling issues and I to find it very
    troublesome to inform the truth on the other hand I’ll certainly come
    again again.

  4. Hi there, I discovered your website by means of Google at the same
    time as looking for a related subject, your web site got
    here up, it seems good. I have bookmarked it in my
    google bookmarks.
    Hi there, simply became alert to your blog via Google, and found
    that it is truly informative. I am gonna be careful for brussels.
    I will be grateful if you happen to continue this in future.
    Numerous other folks can be benefited out of your writing.

    Cheers!

Leave a Reply

Your email address will not be published.